Overview
Trima Accel Automated Blood Collection System Reveos Automated Blood Processing System Welders & Sealers Reliable, sterile connections using cost-effective tubing welders and sealers Whole Blood Bag Systems Whole blood collection, component processing and storage
See all
TOMEs Terumo Operational Medical Equipment Software Trima KPI Dashboard Data visualization and KPIs Cadence Data Collection System Veda Solutions Service | Analytics | Consulting Vista Information System
See all
Overview
Spectra Optia Apheresis System Cell Collections Comprehensive cell collection solutions Red Blood Cell Exchange Therapeutic Apheresis Red Blood Cell Exchange Vascular Access Your resource for optimizing vascular access for each and every patient Sickle Cell Disease Transfusion Therapy for Sickle Cell Disease
See all
Cell Collection Services Spectra Optia Cell Collection Services Veda Solutions Service | Analytics | Consulting
See all
Overview
Quantum Flex Cell Expansion System FINIA Fill and Finish System Welders & Sealers Reliable, sterile connections using cost-effective tubing welders and sealers Spectra Optia Cell Collections Spectra Optia Cell Collection Services
See all
Cell Collection Services Comprehensive cell collection solutions Veda Solutions Service | Analytics | Consulting
See all
Overview
Welders & Sealers Reliable, sterile connections using cost-effective tubing welders and sealers Accessories for Blood Centers Collection, processing and storage needs.
See all
Veda Solutions Service | Analytics | Consulting Contract Manufacturing Innovation and quality in contract manufacturing
See all
Overview
Product Security Product Certificates Safety Data Sheets Technical Documents Patents Trademarks Terms and Conditions
See all
Contact Product Support
See all
Overview
Charitable Donations
See all
Contact Us Medical information request
See all
Overview
eLearning Successions Live From Lakewood Operator Training Technician Training Classes
See all
On-Demand Webinars and Videos Request education and training Request technician training
See all
Overview
Collaborations and Alliances Patient Stories Research and Grant Opportunities Compliance Sustainability Drop of Hope
See all
Executive Leadership Ethylene Oxide and Sterilization in Healthcare Environment, Health, and Safety Policy Non-DEHP Commitment Terumo Integrity Hotline
See all
Overview
Total Rewards Benefits, compensation, and other rewards Diversity and Belonging Committed to a work environment that welcomes differences and unique viewpoints Our Culture Our values are the heart of our culture
See all
Overview
Insights Thought leadership articles Noteworthy Mentions Noteable news publications and mentions News Releases Latest news and updates Media Resources Access media resources
See all
Terumo Global
Terumo Global
Global Blood Solutions

To maintain the highest level of blood safety while keeping costs down, our technologies and software can be implemented and integrated at each step along your supply chain from collection and processing to pathogen reduction and storage.

Learn more
Products
See all
Software & Services
See all
Therapeutic Apheresis

As a global leader in therapeutic apheresis and cell collections, Terumo Blood and Cell Technologies is dedicated to advancing apheresis to help provide more treatment options for the patients you serve.

Learn more
Products, Indications & Protocols
See all
Software & Services
See all
Cell Therapy Technologies

The field of cell therapy is a fast-moving, ever-changing landscape. We take pride in leading the way with comprehensive manufacturing strategies, customized solutions, and performance-focused products, all backed with the expertise and support to help guide your success.

Learn more
Products
See all
Software & Services
See all
Additional Products & Services

Additional offerings from Terumo Blood and Cell Technologies.

Learn more
Products
Software & Services
Product Support

View a variety of helpful links and resources related to our products, including access to the support portal

Learn more
Resources
Inquires
Contact Us

Get in touch with our product support team

Learn more
Work With Us
Inquiries
Training

Explore our variety of online and in-person learning opportunities

Learn more
Training & Classes
Resources
About Us

Read about how we are unlocking the potential of blood- and cell-based therapies, and explore additional resources about our company

Learn more
Our Impact
Our Commitment
Careers

Explore exciting global career opportunities at Terumo Blood and Cell Technologies

Learn more
Work With Us
News & Insights

Stay up-to-date with news, insights, and more

Learn more
News & Events
Location preference

Enter your country so we can show you products that are available for you.

  • Afghanistan   (AF)   |   English
  • Albania   (ALB)   |   English
  • Algeria   (DZ)   |   English
  • Argentina   (AR)   |   English
  • Armenia   (AM)   |   English
  • Australia   (AU)   |   English
  • Austria   (AT)   |   English
  • Azerbaijan   (AZ)   |   English
  • Bahamas   (BS)   |   English
  • Bahrain   (BH)   |   English
  • Bangladesh   (BD)   |   English
  • Barbados   (BB)   |   English
  • Belarus   (BY)   |   English
  • Belgium   (BE)   |   English
  • Belize   (BZ)   |   English
  • Benin   (BJ)   |   English
  • Benin   (GH)   |   English
  • Bhutan   (BT)   |   English
  • Bolivia   (BO)   |   English
  • Bosnia Herzegovina   (BA)   |   English
  • Brazil   (BR)   |   English
  • Brunei   (BN)   |   English
  • Bulgaria   (BG)   |    English
  • Cambodia   (KH)   |   English
  • Canada   (CA)   |   English
  • Chile   (CL)   |   English
  • China   (CN)   |   中文
  • Columbia   (COL)   |   English
  • Costa Rica   (CR)   |   English
  • Cote d'ivoire   (CI)   |   English
  • Croatia   (HR)   |   English
  • Cuba   (CU)   |   English
  • Cyprus   (CY)   |   English
  • Czech Republic   (CZ)   |   English
  • Denmark   (DK)   |   English
  • Dominican Republic   (DO)   |   English
  • Ecuador   (EC)   |   English
  • Egypt   (EG)   |   English
  • El Salvador   (SV)   |   English
  • Eritrea   (ERI)   |   English
  • Estonia   (EE)   |   English
  • Ethiopia   (ET)   |   English
  • Fiji   (FJ)   |   English
  • Finland   (FI)   |   English
  • France   (FR)   |   English
  • French Guiana   (GF)   |   English
  • Georgia   (GE)   |   English
  • Germany   (DE)   |   English
  • Global   |   English
  • Greece   (GR)   |   English
  • Guatemala   (GT)   |   English
  • Haiti   (HT)   |   English
  • Honduras   (HN)   |   English
  • Hong Kong SAR, China   (HK)   |    中国人
  • Hungary   (HU)   |   English
  • Iceland   (IS)   |   English
  • India   (IN)   |   English
  • Indonesia   (ID)   |   English
  • Iran   (IR)   |   English
  • Iraq   (IQ)   |   English
  • Ireland   (IE)   |   English
  • Israel   (IL)   |   English
  • Italy   (IT)   |   English
  • Jamaica   (JM)   |   English
  • Japan   (JP)   |   日本語
  • Jordan   (JO)   |   English
  • Kazakhstan   (KZ)   |   English
  • Kenya   (KE)   |   English
  • Kuwait   (KW)   |   English
  • Kyrgyzstan   (KG)   |   English
  • Laos   (LA)   |   English
  • Latvia   (LV)   |   English
  • Lebanon   (LB)   |   English
  • Liberia   (LR)   |   English
  • Libya   (LY)   |   English
  • Liechtenstein   (LI)   |   English
  • Lithuania   (LT)   |   English
  • Luxembourg   (LU)   |   English
  • Macedonia   (MK)   |   English
  • Malaysia   (MY)   |   English
  • Maldives   (MV)   |   English
  • Malta   (MT)   |   English
  • Mauritius   (MU)   |   English
  • Mexico   (MX)   |   English
  • Moldova   (MD)   |   English
  • Mongolia   (MN)   |   English
  • Montenegro   (ME)   |   English
  • Morocco   (MAR)   |   English
  • Mozambique   (MZ)   |   English
  • Myanmar   (MM)   |   English
  • Namibia   (NA)   |   English
  • Nepal   (NP)   |   English
  • Netherlands   (NL)   |   English
  • Netherlands Antilles   (AN)   |   English
  • New Caledonia   (NC)   |   English
  • New Zealand   (NZ)   |   English
  • Nicaragua   (NIC)   |   English
  • Nigeria   (NG)   |   English
  • Norway   (NO)   |   English
  • Oman   (OM)   |   English
  • Pakistan   (PK)   |   English
  • Palestine   (PS)   |   English
  • Panama   (PA)   |   English
  • Papua New Guinea   (PG)   |   English
  • Paraguay   (PY)   |   English
  • Peru   (PE)   |   English
  • Philippines   (PH)   |   English
  • Poland   (PL)   |   English
  • Portugal   (PT)   |   English
  • Puerto Rico   (PR)   |   English
  • Qatar   (QA)   |   English
  • Romania   (RO)   |   English
  • Russia   (RU)   |   English
  • Saudia Arabia   (SA)   |   English
  • Senegal   (SN)   |   English
  • Serbia   (RS)   |   English
  • Seychelles   (SC)   |   English
  • Singapore   (SG)   |   English
  • Slovakia   (SK)   |   English
  • Slovenia   (SI)   |   English
  • Solomon Islands   (SB)   |   English
  • South Africa   (ZA)   |   English
  • Spain   (ES)   |   English
  • Sri Lanka   (LK)   |   English
  • Sudan   (SD)   |   English
  • Sweden   (SE)   |   English
  • Switzerland   (CH)   |   English
  • Syria   (SY)   |   English
  • Taiwan, Province of China   (TW)   |    中国人
  • Tajikistan   (TJ)   |   English
  • Thailand   (TH)   |   English
  • Timor-Leste   (TL)   |   English
  • Togo   (TG)   |   English
  • Trinidad and Tobago   (TT)   |   English
  • Tunisia   (TN)   |   English
  • Turkey   (TR)   |   English
  • Turkmenistan   (TM)   |   English
  • Ukraine   (UA)   |   English
  • United Arab Emirates   (UAE)   |   English
  • United Kingdom   (GB)   |   English
  • United States   (US)   |   English
  • Uruguay   (UY)   |   English
  • Uzbekistan   (UZ)   |   English
  • Vietnam   (VN)   |   English
  • Yemen   (YE)   |   English
  • Zambia   (ZM)   |   English

Spectra Optia Exchange Protocols

Supporting multiple patient needs with exchange therapies

The Spectra Optia™ Apheresis System from Terumo Blood and Cell Technologies offers a range of exchange therapy protocols.* Browse the information below for details. If you have questions, please reach out to our apheresis device and procedure experts.  

Exchange

Procedure information

  • 87% (± 3%) mean plasma removal efficiency1
  • 1.15 total blood volumes (TBVs) to remove one plasma volume2
  • 14.4 mL anticoagulant (AC) per L of whole blood processed3
  • Optimized fluid balance enabled by pump precision
  • 1.0% median patient platelet loss1
  • Typical extracorporeal volume (ECV) is 141 mL; maximum ECV is 185 mL**
  • Intuitive procedure management

Automated Interface Management (AIM™) System

Featured resources

Disclaimers and notes

1. Tormey CA, et al. Transfusion. 2010; 50 (2): 471-477. doi: 10.1111/j.1537-2995.2009.02412.x. 

2. Calculation: 1/0.87 = 1.15

3. Calculations: 
Anticoagulant volume = 1,000 mL/9 (inlet:AC ratio of 10 = 9 parts blood to 1 part AC) = 111 mL 
Spectra Optia system: 100% − 87% = 13% of 111 mL = 14.4 mL AC/L processed 
Assumptions: AC ratio of 10

Note: An AC infusion rate of 0.8 to 1.2 mL/min/L TBV was used during the clinical studies; however, it was not used directly in this calculation.

**Under normal operating conditions, the ECV will not exceed the typical ECV value. Under certain infrequent alarm conditions, such as during reservoir recovery after a reservoir alarm, the ECV may momentarily increase to the maximum ECV value.

Procedure information

  • Provides adjustable plasma flow rates to accommodate a range of SPDs²
  • Monitors and displays pressure readings for the SPD with a pressure sensor
  • Provides an optimized product for secondary processing with a mean plasma removal efficiency of 87% ± 3%³
  • Offers the option to pause the system for added flexibility, enabling more focus on the patient
  • Features dynamic technology that delivers consistent, predictable results when performing TPE with an SPD
  • Typical extracorporeal volume (ECV) is 141 mL; maximum ECV is 185 mL**

Graphical user interface (GUI) for TPE with SPD procedure

Featured resource

Disclaimers and notes

1. Secondary plasma devices may be used with flow rates from 10 mL/min to 100 mL/min on the Spectra Optia system.

2. Check secondary plasma device specifications for requirements.

3. Tormey CA, et al. Transfusion. 2010; 50 (2): 471-477. doi: 10.1111/j.1537-2995.2009.02412.x.

**Under normal operating conditions, the ECV will not exceed the typical ECV value. Under certain infrequent alarm conditions, such as during reservoir recovery after a reservoir alarm, the ECV may momentarily increase to the maximum ECV value.

Procedure information

  • Requires no additional hardware; only a Y-connector is needed
  • Features the flexibility to utilize single-needle access from the onset of the procedure or at any time during the procedure
  • Makes the transition to single-needle access simple with minimal setup time and no loss in system mobility
  • Guides you with intuitive touch screens specific to the single-needle option 
  • Typical extracorporeal volume (ECV) is 141 mL; maximum ECV is 185 mL**

Graphical user interface (GUI) for TPE with single-needle access

Y-connector for use with the Spectra Optia Exchange Set  

Featured resource

Disclaimers and notes

**Under normal operating conditions, the ECV will not exceed the typical ECV value. Under certain infrequent alarm conditions, such as during reservoir recovery after a reservoir alarm, the ECV may momentarily increase to the maximum ECV value.

 

Procedure information

  • Performs exchange, depletion, or depletion/exchange procedures
  • Accommodates small patients with a 185 mL tubing set
  • Streamlines procedures, enabling operators to spend more time with patients
  • Displays a clearly defined custom prime sequence that differentiates blood priming from the actual procedure 
  • Provides intuitive procedure management
  • Typical extracorporeal volume (ECV) is 141 mL; maximum ECV is 185 mL**

Graphical user interface (GUI) for the RBCX protocol

Featured resources

Disclaimers and notes

**Under normal operating conditions, the ECV will not exceed the typical ECV value. Under certain infrequent alarm conditions, such as during reservoir recovery after a reservoir alarm, the ECV may momentarily increase to the maximum ECV value.

 

See how the Spectra Optia system can be the solution to your apheresis and cell collection needs.

Connect with our experts

Explore other protocols available on Spectra Optia

Spectra Optia protocols
Collection
Learn more
Spectra Optia protocols
Depletion
Learn more
Spectra Optia protocols
Processing
Learn more

Contraindications

  • There are no known contraindications for the system's use, except for those associated with all automated apheresis systems.
  • The infusion of certain solutions and replacement fluids may be contraindicated in some patients.

Possible patient reactions

  • Anxiety, headache, light-headedness, digital and/or facial paresthesia, fever, chills, hematoma, hyperventilation, nausea and vomiting, syncope (fainting), urticaria, hypotension, and allergic reactions.

Reactions to transfused blood products can include1

  • Fever, circulatory overload, shock, allergic reactions, alloimmunization, graft-versus-host disease, and transmission of infection.

Restricted to prescription use only

  • Operators must be familiar with the system's operating instructions.
  • Procedures must be performed by qualified medical personnel.
  • A supervisory practitioner may supervise from a physician office or other nonhospital space that is not officially part of the hospital campus as long as he or she remains immediately available.2

 

1. AABB (ed.), et al. Circular of Information for the Use of Human Blood and Blood Components. 10th ed. 2006; Council of Europe Publishing, Seattle, WA.

2. American Society for Apheresis. Guidelines for documentation of therapeutic apheresis procedures in the medical record by apheresis physicians. J Clin Apher. 2007;22(3):183. 

Disclaimers and notes

*Product and protocol availability varies by country.

 

To top